JOINT RESEARCH
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Collaborative Research and Development
Solve challenges with the SENTAN platform. Why not unlock your compound's potential?
Consult us about compounds like these:
・Difficult to scale up
・Particle size is not uniform
・Want to control release speed
・Want to handle everything from initial studies to GMP manufacturing
・Considering transition to GMP manufacturing
- Development abandoned due to strong side effects
- Seeking improved dispersibility for poorly soluble components
- Considering nanoparticle formulations but...
・Difficult to scale up
・Particle size is not uniform
- Considering microparticle formulations but...
・Want to control release speed
・Want to handle everything from initial studies to GMP manufacturing
・Considering transition to GMP manufacturing
Nanoparticle Formulation Feasibility Study Basic Package
1. Investigation of optimal conditions for compound nanoparticle formulation
3. Delivery of nanoparticles manufactured under optimal conditions
4. Submission of final report
2. Report on physical property evaluation results
・Concentration ・ Particle size distribution ・ Powder X-ray diffraction
3. Delivery of nanoparticles manufactured under optimal conditions
4. Submission of final report
Options(additional to basic set):
・Dissolution rate ・AUC ・Zeta potential ・DSC thermal analysis ・TEM (transmission electron microscopy) image
■ Items to be prepared by the customer at contract signing
［ Compound, quantitative method measurement conditions, HPLC / GC column ］
■ Compounds Well-Suited for Nanotechnology:
［ Lipophilic, poorly soluble compounds ］
Feasibility Study for Microparticle Formulation of Long-Acting Sustained-Release Injections: Basic Set
1. Evaluation of the Effect of Polymer Type
2. Evaluation of the Effect of Drug Loading Rate
3. Final Formulation Evaluation
[Evaluation Content]・Formulation Preparation
・Physical Property Evaluation (Particle Size, Content Measurement)・Release Profile Evaluation
・Physical Property Evaluation (Particle Size, Content Measurement)・Release Profile Evaluation
4. Final Report Submission
Options(Add-ons to Basic Package)
・Drug Plasma Concentration Measurement
■ Items to be Prepared by the Client at Contract Signing
［ Compounds, quantitative measurement methods, HPLC / GC columns ］
■ Features
・ Sustained-release functionality can be incorporated (1 to 3 months)
・ Through partnerships with domestic CMO companies, scale-up studies and GMP manufacturing are possible